Panhandle Plains Vacations

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Your Panhandle Plains Vacation

Panhandle Plains's rugged landscapes and rich traditions are just the beginning of the great things this destination has to offer travelers. Get the best out of your retreat by pulling together your own Panhandle Plains vacation package. Your trip to Panhandle Plains wouldn't be complete without getting to some of its most well-known cities, starting with Amarillo. Two of the top attractions here include Cadillac Ranch and Wonderland Amusement Park. Lubbock is another favorite with Panhandle Plains travelers. Visitors to this exciting destination enjoy Buddy Holly Center and United Supermarkets Arena. Expedia has everything you need when it comes to organizing your Panhandle Plains vacation. From accommodations and flights, to car rentals and activities, we know how to create a travel experience like no other.

Where to stay in Panhandle Plains

Find the best Panhandle Plains areas and neighborhoods for the activities you enjoy most. Learn more about Panhandle Plains

Discover the most popular places to visit in Panhandle Plains

Panhandle Plains Hotel Deals

Baymont by Wyndham Amarillo East

Baymont by Wyndham Amarillo East

2.5 out of 5
1700 I-40 E, Amarillo, TX
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $71 total per night from Sep 1 to Sep 2
$71 total
Sep 1 - Sep 2
Total with taxes and fees
8.4/10 Very Good! (1,590 reviews)
"We liked the clean rooms, friendly staff, parking and close walking distance t o Denny's."

Reviewed on Aug 20, 2025

Baymont by Wyndham Amarillo East
Holiday Inn Express & Suites Amarillo West by IHG

Holiday Inn Express & Suites Amarillo West by IHG

2.5 out of 5
8330 W Amarillo Blvd, Amarillo, TX
Fully refundable
$100 nightly
The price is $115 total per night from Sep 24 to Sep 25
$115 total
Sep 24 - Sep 25
Total with taxes and fees
9.2/10 Wonderful! (1,789 reviews)
"Nice rooms and property. Dog friendly."

Reviewed on Aug 23, 2025

Holiday Inn Express & Suites Amarillo West by IHG
The Cactus Cove Inn and Suites

The Cactus Cove Inn and Suites

2 out of 5
2501 E Interstate Dr, Amarillo, TX
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $102 total per night from Aug 26 to Aug 27
$102 total
Aug 26 - Aug 27
Total with taxes and fees
7.8/10 Good! (1,911 reviews)
One night In Amarillo
"The hotel I believe was a Crown Plaza. Back in it hay day. They remodeled the bathroom and bed area . But signs of wear and turn were all over. The bed was comfortable and the bathroom clean. Cheap or free breakfast. It was a nice inexpensive room. I would stay again if I just needed to sleep."

Reviewed on Aug 23, 2025

The Cactus Cove Inn and Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.